Bone Broth Side Effects: What's Normal, What's Not, and How to Adjust

I am going to do something here that I do not always see bone broth brands do: I am going to be completely honest with you about the fact that bone broth can, in some people, cause digestive responses. Especially in the beginning.

I say this as someone who has recommended bone broth to thousands of patients and customers. I believe in it deeply. But I also believe in giving you the full picture so you can make smart decisions for your own body. So let's talk about what side effects some people experience, why they happen, and what to do about them.

The Good News First

The vast majority of people who drink bone broth experience no adverse effects whatsoever. Many feel noticeably better within days: less bloating, better digestion, more energy, clearer skin. For most people, bone broth is one of the most gentle, nourishing things they can add to their diet. But some people do experience a digestive adjustment period, particularly in the first week or two. And a smaller subset have specific sensitivities to compounds in bone broth that are worth knowing about.

Can Bone Broth Cause Diarrhea?

This is the most common side effect question I receive, so let me address it directly. Yes, some people experience loose stools or changes in bowel habits when they first start drinking bone broth, particularly in larger amounts. There are two main reasons. First, the high glycine content of bone broth can have a mild laxative effect in some individuals when consumed in larger servings. Second, bone broth changes the environment of your gut microbiome, and any significant dietary change can temporarily affect bowel habits. The solution is almost always the same: start with a half cup rather than a full cup and build up gradually over a week or two as your body adjusts.

Histamine Sensitivity and Bone Broth

This is the most important side effect to know about. Long-simmered bone broth is naturally high in histamines. For people with histamine intolerance, bone broth can trigger symptoms including headaches, skin flushing, digestive discomfort, or runny nose. I wrote a full guide on histamine intolerance that is worth reading if you suspect this might apply to you. The adjustments that help most: choose a fresher or shorter-simmered broth, make your own and use it immediately, or start with very small amounts and observe your response carefully.

Changes in Bowel Habits

Some people report temporary constipation when starting bone broth. The most frequent cause is simply not drinking enough water alongside your bone broth intake. Make sure you are drinking at least 64 ounces of water per day, more if you are active. Adequate hydration is important whenever you increase your protein intake.

Sodium Concerns

Bone broth can vary significantly in sodium content depending on the product. For most healthy people, this is not a concern in a one-to-two cup daily serving. But if you are monitoring your sodium intake for blood pressure or kidney health reasons, check the label and factor it into your total daily count.

What About Lead and Heavy Metals?

Some older studies raised questions about lead content in certain bone broths, particularly those made from conventional, non-grass-fed bones. Here is the important nuance: the source and quality of the bones matters enormously. Bones from grass-fed, pasture-raised animals living in clean environments have significantly lower heavy metal accumulation. This is one of the most important reasons I have always been strict about the sourcing standards for my bone broth: what goes into the bones ends up in your cup.

How Much Bone Broth Is Too Much?

Most side effects from bone broth are related to consuming too much too soon rather than any inherent problem with the broth itself. I cover the right daily serving guidelines in detail in my post on how much bone broth per day: the general principle is to start with one cup per day, see how your body responds for a week, and then increase to two cups if you are feeling good. Gradual introduction gives your body time to adjust.

Who Should Be Especially Cautious

While bone broth is safe and beneficial for the vast majority of people, these groups should consult a healthcare provider before making it a daily habit:

• People on medications for blood pressure, blood sugar, or kidney disease

• People with known histamine intolerance

• People with a history of kidney stones

• Pregnant women (ensure products are from quality, tested sources)

When to Stop and Reach Out to a Provider

Most side effects from bone broth are mild and resolve within one to two weeks as your body adjusts. However, if you experience persistent diarrhea lasting more than a week despite reducing your serving size, significant skin reactions like hives or rash, headaches or palpitations that worsen over time, or any symptom that concerns you, stop and consult a healthcare provider. Trust your body. It is good at telling you what it needs.

The Bottom Line

Bone broth side effects exist, and I think you are better served knowing about them honestly than being surprised by them. For most people, any initial adjustment is mild, temporary, and easily managed by starting with smaller servings and staying hydrated. Start gently with Dr. Kellyann's bone broth, listen to your body, and give yourself the grace of an adjustment period. And if you want the full framework for using bone broth as part of a structured clean eating approach, my Bone Broth Diet gives you the complete daily plan that thousands of my patients and customers have used to get real, lasting results.