Collagen During Pregnancy: A Complete Guide for Expecting Moms

by Kellyann Petrucci
Table of Contents

    Pregnancy puts unprecedented demand on a woman's connective tissue. Your skin stretches, your ligaments loosen, your bones support more weight, and your body is growing an entirely new human while maintaining everything you already had. The structural proteins that hold your body together are working overtime, and the raw material they need to function comes from the protein and amino acids in your diet. Collagen is one of the most studied supplemental supports for this demand, and many expecting moms are now incorporating it as a daily anchor in their prenatal nutrition.

    I want to walk you through what collagen actually does during pregnancy, how to incorporate it through each trimester, and the considerations that matter for choosing the right product. Our Collagen Peptides Unflavored is a single-ingredient hydrolyzed collagen, which is the cleanest profile for evaluating during pregnancy. As always, this is general information, not a substitute for the conversation you should have with your own OB or midwife about your specific situation.

    Why Collagen Demand Climbs During Pregnancy

    Collagen is the most abundant protein in your body, and pregnancy demands an enormous increase in its production. Your skin must stretch significantly, particularly across the abdomen and breasts. The uterus expands to many times its normal size. The placenta grows from nothing into a full functioning organ. Your ligaments loosen under the influence of relaxin, which means they are being remodeled actively. All of this requires fresh collagen synthesis at rates the non-pregnant body never approaches.

    Your body uses dietary amino acids to build this new collagen. The most critical amino acids are glycine, proline, and hydroxyproline, all of which are richly present in supplemental collagen peptides. Whether you get them from collagen specifically or from collagen-rich whole foods like bone broth, what matters is that the supply meets the demand during these months.

    The Glycine Question in Pregnancy

    Glycine deserves special attention in any pregnancy nutrition conversation. Glycine is normally considered non-essential because the body can make it from other amino acids. But during pregnancy, the body's demand for glycine often exceeds its ability to produce it, especially in the third trimester. This makes glycine conditionally essential during pregnancy, which is a more important distinction than the casual conversation usually acknowledges.

    Glycine is required for fetal DNA synthesis, collagen production in developing tissues, and the formation of the placenta itself. Some research suggests that inadequate maternal glycine intake may be associated with smaller birth weights and certain pregnancy complications. Collagen peptides are one of the richest dietary sources of glycine, which is part of why collagen is so well-suited to prenatal supplementation.

    Trimester-by-Trimester Approach

    During the first trimester, nausea is often the dominant feature. Many women find that hot beverages worsen the nausea, so collagen mixed into cold water, apple juice, or coconut water is often more tolerable. The dose can be modest during this window (5 to 10 grams per day) because the structural demand is just beginning to ramp up.

    The second trimester brings returning appetite and increasing physical demands. This is when collagen incorporation typically becomes easier and more rewarding. Smoothies, oatmeal, soups, and warm beverages all work well as collagen delivery methods. The dose can increase to 10 to 15 grams per day to support the growing structural demand.

    The third trimester is when glycine and collagen demand peaks. The baby is growing rapidly, the placenta is fully developed, and maternal connective tissues are under maximum stretch. Continuing 10 to 15 grams of collagen daily, ideally combined with bone broth several times a week, supports the body through this most demanding window.

    Combining Collagen With Bone Broth

    Many pregnant women find that combining collagen supplementation with bone broth produces the most complete connective tissue support. Bone broth delivers a similar amino acid profile in a whole-food format, plus additional minerals (calcium, phosphorus, magnesium) and gelatin that supplement powders do not contain. Our bone broth collection is built on grass-fed, slow-simmered bones that produce a richer nutritional profile than typical commercial broths.

    The Bone Broth Diet framework provides structure for incorporating bone broth into daily eating, though the strict cleanse aspects of any diet are not appropriate during pregnancy. Discuss with your healthcare provider before following any restrictive eating pattern while pregnant. For most expecting moms, the practical approach is a daily collagen scoop plus several cups of bone broth per week, integrated into the broader prenatal nutrition strategy.

    Choosing a Pregnancy-Safe Collagen

    Not all collagen products are equally appropriate during pregnancy. The cleanest choice is single-ingredient hydrolyzed collagen with no added botanicals, herbs, hormones, or unfamiliar compounds. Third-party tested products with verified absence of heavy metals are important, since some lower-quality collagen has been found to contain traces of lead.

    Products from grass-fed bovine or wild-caught marine sources tend to have cleaner profiles. Avoid collagen products that contain added ingredients you would not knowingly consume during pregnancy: herbal blends, hormonal-acting plant compounds, high-dose vitamins, stimulants, or unusual functional ingredients. The simpler the supplement facts panel, the safer the evaluation.

    Stretch Marks and Skin Elasticity

    One of the most common reasons women take collagen during pregnancy is to support skin elasticity and potentially reduce stretch marks. The research on stretch marks specifically is limited, but the underlying biology makes sense. Stretch marks form when the dermis tears under rapid stretching, and the body uses collagen to repair those tears. Adequate dietary collagen during pregnancy gives the body the raw material for this repair process.

    Combined with topical care (gentle moisturizing of stretching areas), staying well-hydrated, and gradual weight gain, dietary collagen is one of the supportive habits worth incorporating. Our collagen and hydration for skin post covers the broader skin support picture.

    Postpartum Considerations

    The collagen routine that supports pregnancy continues to be valuable in the postpartum period. The body is recovering from significant structural changes, the skin is contracting back from its stretched state, and the demands of breastfeeding (if applicable) add their own nutrient requirements. Many women find that the collagen routine they started during pregnancy becomes even more valuable in the months after delivery.

    Our companion post on bone broth vs collagen covers another useful comparison for the postpartum window, when you may be deciding which form of connective tissue support fits best with your recovery routine.

    A Reasonable Pregnancy Collagen Routine

    If you want a simple framework, here it is. Discuss Collagen Peptides with your OB or midwife before starting (most providers have no concerns about clean hydrolyzed collagen). Begin with 5 to 10 grams per day in the first trimester, adjusting up to 10 to 15 grams as appetite returns. Combine with a cup of bone broth several times a week. Pair with adequate hydration, balanced meals, and the rest of your prenatal nutrition routine. The compounded result over nine months is meaningful support for the structural demands your body is facing.

    Frequently Asked Questions

    Is Collagen Peptides safe during the first trimester?

    Collagen Peptides is generally considered appropriate during the first trimester, but always discuss any new supplement with your OB or midwife before starting. During the nausea-heavy first trimester, many women find it easier to take a smaller dose mixed into cold liquids until appetite returns in the second trimester.

    Can Collagen Peptides be combined with prenatal vitamins?

    Yes, Collagen Peptides can be taken alongside prenatal vitamins without any known interactions. The two work on different aspects of nutrition (Collagen Peptides for connective tissue support, prenatals for the broader vitamin and mineral needs), so they complement rather than compete.

    Does Collagen Peptides help prevent stretch marks?

    Research specifically on Collagen Peptides and stretch marks is limited, but the amino acids in Collagen Peptides support the body's collagen synthesis that helps skin repair as it stretches. Combined with gentle moisturizing, gradual weight gain, and good hydration, Collagen Peptides may help support skin elasticity, though results may vary.

    What is the best way to take Collagen Peptides if I have pregnancy nausea?

    Cold or room-temperature liquids tend to be most tolerable during nausea-heavy windows. Try mixing Collagen Peptides into cold water with a splash of apple juice, coconut water, or fruit smoothies. Hot beverages can sometimes worsen nausea in the first trimester, so save those for later in pregnancy when nausea has eased.

    These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Results may vary by individual. Consult your healthcare provider before adding any new supplement to your routine.

     

    Dr. Kellyann Petrucci

    About the Author

    Dr. Kellyann Petrucci

    M.S., N.D. · Board-Certified Naturopathic Physician · New York Times Bestselling Author

    Dr. Kellyann Petrucci is a board-certified naturopathic physician, certified nutrition consultant, and New York Times bestselling author with over 20 years of clinical experience. She is the creator of the Bone Broth Diet and Cleanse + Reset programs, and author of multiple bestselling books including Dr. Kellyann's Bone Broth Diet, The 10-Day Belly Slimdown, and The Bone Broth Breakthrough.

    Dr. Kellyann completed postgraduate work in biological medicine at the Paracelsus Clinic in Switzerland and is a regular health expert on Good Morning America, The Dr. Oz Show, Good Day LA, and other nationally televised programs. She is also the host of two PBS specials: 21 Days to a Slimmer, Younger You and The 10-Day Belly Slimdown.